Endocrine Abstracts

Introduction: Opportunistic infections are a recognised complication of severe hypercortisolism. We report a case of Pneumocystis Pneumonia (PCP for formerly named Pneumocystis carinii pneumonia) in patient with ectopic Cushing's syndrome (CS) caused by a metastatic neuroendocrine carcinoma of the lung.Case history: A 61-year old male attended the Acute Medical Unit for investigation and treatment of seve...

Introduction: Opportunistic infections are a recognised complication of severe hypercortisolism. We report a case of Pneumocystis Pneumonia (PCP for formerly named Pneumocystis carinii pneumonia) in patient with ectopic Cushing's syndrome (CS) caused by a metastatic neuroendocrine carcinoma of the lung.Case history: A 61-year old male attended the Acute Medical Unit for investigation and treatment of seve...

Introduction: Hypoglycaemia following bariatric surgery is a recognised complication, secondary to increased incretin secretion to nutrient intake due to altered gut anatomy. It is predominantly postprandial, and usually occurs >6 months postoperatively. We report a case of insulinoma unmasked during the early postoperative period after sleeve gastrectomy (SG).Case presentation: A 49-year old female with severe obesity without diabetes underwent SG. ...

A 21 year old Asian woman presented with relapse of Neuromyelitis Optica (NMO) spectrum disorder, diagnosed aged 16. She had headache, dizziness, right hand weakness and severe hyponatraemia (serum sodium [Na+] 116 [135–145]). Emesis, dominant in previous relapses, was absent – she was euvolaemic. Serum (Seosm) and urine (Uosm) osmolalities were 250 and 468 mosm/kg respectively, thyroid function ...

A 21 year old Asian woman presented with relapse of Neuromyelitis Optica (NMO) spectrum disorder, diagnosed aged 16. She had headache, dizziness, right hand weakness and severe hyponatraemia (serum sodium [Na+] 116 [135–145]). Emesis, dominant in previous relapses, was absent – she was euvolaemic. Serum (Seosm) and urine (Uosm) osmolalities were 250 and 468 mosm/kg respectively, thyroid function ...

Aim: To measure Urocortin3 (Ucn3) blood levels in morbidly obese (MO) non diabetic patients before and after laparoscopic sleeve gastrectomy (LSG) for excess body weight reduction and explore its relationship with b-cell function. Ucn3 is involved in insulin secretion in the presence of nutrient excess, a key feature of obesity, and may be an integral part of the compensation of β-cells function.Methods: Nine MO patients who underwent LSG and 11 hea...